A Beautifully Illustrated Open Access Review Article on DNA Topoisomerases

first_img Intelligent Design A Beautifully Illustrated Open Access Review Article on DNA TopoisomerasesPaul NelsonJanuary 25, 2021, 11:46 AM Email Print Google+ Linkedin Twitter Share Photo source: Science Museum, London / Science and Society Picture Library, CC BY-SA 2.0 , via Wikimedia Commons.Good review articles are pure gold, especially when they’re open access. Here is one. See, “DNA topoisomerases: Advances in understanding of cellular roles and multi-protein complexes via structure-function analysis.” It’s design triangulation, although both Crick and Watson would scream No. That’s okay; their actions in publication belie their personal philosophies. Evolution Jane Goodall Meets the God Hypothesis A biochemistry friend who works with topoisomerases told me years ago that Crick and Watson realized, very early on, that the winding double helix of DNA would cause all kinds of nasty tangles. In their second Nature paper (1953), however, on the “Genetical Implications of the Structure of Deoxyribonucleic Acid” (May 30), they noted: Paul NelsonSenior Fellow, Center for Science and CulturePaul A. Nelson is currently a Senior Fellow of the Discovery Institute and Adjunct Professor in the Master of Arts Program in Science & Religion at Biola University. He is a philosopher of biology who has been involved in the intelligent design debate internationally for three decades. His grandfather, Byron C. Nelson (1893-1972), a theologian and author, was an influential mid-20th century dissenter from Darwinian evolution. After Paul received his B.A. in philosophy with a minor in evolutionary biology from the University of Pittsburgh, he entered the University of Chicago, where he received his Ph.D. (1998) in the philosophy of biology and evolutionary theory.Follow PaulProfile Share Congratulations to Science Magazine for an Honest Portrayal of Darwin’s Descent of Man Origin of Life: Brian Miller Distills a Debate Between Dave Farina and James Tourcenter_img Since the two chains in our model are intertwined, it is essential for them to untwist if they are to separate. As they make one complete turn around each in 34 A., there will be about 150 turns per million molecular weight, so that whatever the precise structure of the chromosome a considerable amount of uncoiling would be necessary. It is well known from microscopic observation that much coiling and uncoiling occurs during mitosis, and  though this is on a much larger scale it probably reflects similar processes on a molecular level. Although it is difficult at the moment to see how these processes occur without everything getting tangled, we do not feel that this objection will be insuperable. A Physician Describes How Behe Changed His MindLife’s Origin — A “Mystery” Made AccessibleCodes Are Not Products of PhysicsIxnay on the Ambriancay PlosionexhayDesign Triangulation: My Thanksgiving Gift to All Tagsbiochemistrychromosomedeoxyribonucleic aciddesign triangulationDNAFrancis CrickJames WatsonNature (journal)review articletopoisomerases,Trending I love that last clause: “…we do not feel that this objection will be insuperable.” No, indeed, because organisms are solving their topological problems, somehow. Not to worry. The system as a whole will have the functional difficulty covered. “A Summary of the Evidence for Intelligent Design”: The Study Guide Our Debt to the Scientific Atheists Recommended Email Print Google+ Linkedin Twitter Sharelast_img read more

RFMD® Announces ITC Lawsuit Withdrawn By Plaintiffs

first_imgRF Micro Devices, Inc. announced that Peregrine Semiconductor Corp. (PSMI) has filed a motion to voluntarily withdraw the lawsuit it filed against RFMD in the U.S. International Trade Commission (ITC) in February 2012. RFMD believes the decision by Peregrine to terminate the ITC proceeding is in response to developments in the case that have consistently validated RFMD’s longstanding position that no infringement of Peregrine’s patents occurred, and that the validity of the asserted Peregrine patents is clearly in doubt. RFMD respects the intellectual property rights of others and takes care to avoid infringements. RFMD has a strong intellectual property portfolio relating to RFICs and switching technology that RFMD has developed over many years. The Company is fully committed to its industry-leading product portfolio and plans to continue to vigorously defend its position in the companion case filed by Peregrine in April 2012 in the U.S. District Court for the Southern District of California. For more information visit http://www.rfmd.com/last_img read more

PNG off to youth challenge

first_imgBasketball BY KEVIN TEME The PNG teams for both the girls and the boys leaves tomorrow to take part in the 2019 FIBA U17 Youth Oceania Championships in Noumea, New Caledonia. The tournament will be held from August 18-24. Basketball Federation of PNG chief executive officer Stephen Damien confirmed in an email yesterday that all the players will assemble in Port Moresby today. The players include a boy from Daru, Western; three girls from Alotau, Milne Bay and the Port Moresby-based players who will be at the Taurama Aquatic Centre for a final briefing. The PNG side also includes four overseas-based players, among them a female, who will join the rest of the side at the Brisbane International Airport before heading to Noumea. It is believed that boys with talent from Alotau and Lae who made it to the Under 15 championship last year have been dropped from the final side. FIBA Oceania president Burton Shipley said it is an elite championship for the 2002 age group in Oceania region. The event will see the best young talents from around the Oceania region come together for six days of tight competition. PNG, which is among eight countries competing at the event, is pooled in group B along with Cook Islands, New Caledonia and Tahiti for the men’s while for the women, PNG is slotted in group B with host New Caledonia, Cook Islands and Tahiti. PNG plays its first game against Tahiti at 6pm next Monday while the girls face off with New Caledonia at 5pm. The final team in the boys division: Torres Koiti (Dari, WP), Morea Elavo, Frank Kaisa, Ray Whitchurch, Harold Elavo, Charlie Bradley, David Kaia, Sammy Baea, Daniel Willie (Port Moresby), Patien Smare, Jimmy Struik and Ethan Tsiamalili (Brisbane). The non-travelling reserves: Martin Ben, Opex Kima, Beaiah John (Port Moresby) and Edwin Kantau from Alotau. The team is coached by Tubs O’Riley while his assistant is Purari Muri. The girls team is a balance of team Alotau (4), Port Moresby (9) including the non travelling reserves, one from Lae and another from Perth. The squad which will be coached by Jennifer Mararo and her assistant Susan Paisoi is Kalista Kotoveke, Sandy Bagela, Jessica Kake, Princess Kaore, Jackie Asiba, Brylie Faso (Port Moresby), Magdelene Javaporo (Perth), Bianca Tuckayo (Lae), Jeleena Irofe, Philomena Isei and Alice Kaiawa (Alotau). The non- traveling reserves are Bianca Nala, Dorcas Talu and Juanita Ipai (Port Moresby). The head of delegation is BFPNG President Nick Daroa.last_img read more

Carlo Ancelotti: Me and Iker Casillas will be at Real Madrid next season

first_imgCarlo Ancelotti says he sees himself at Real Madrid next season, along with Iker Casillas. 17/04/2015 Upd. at 21:36 He also defended the goalkeeper, amid claims David De Gea may join from Manchester United next season. CEST Sport EN But Ancelotti said: “I see myself here at Real Madrid next season, with Casillas and with all of the others who are doing a good job. It’s not an important question at this point in time. We are focused on what we need to do.” The Italian coach may find himself in hot water at the Santiago Bernabeu if he cannot bring either La Liga or the eleventh Champions League to the table at the end of the season.  “It’s not for me to list a ranking of goalkeepers; I have three very good goalkeepers who I am happy with. The best goalkeepers in the world are the ones I have in my squad. I’ve never spoken about signing another goalkeeper.”last_img read more

Statement from Premier Daniel Andrews

first_imgPremier DANIEL ANDREWS released a statement to the media on Sunday 17 May, advising cafes, restaurants and pubs will be…[To read the rest of this story Subscribe or Login to the Gazette Access Pass] Thanks for reading the Pakenham Berwick Gazette. Subscribe or Login to read the rest of this content with the Gazette Digital Access Pass subscription.last_img

Victims in A.V. lose thousands in lottery scam

first_img AD Quality Auto 360p 720p 1080p Top articles1/5READ MOREFrumpy Middle-aged Mom: My realistic 2020 New Year’s resolutions. Some involve doughnuts.Sheriff’s detectives are investigating the scam, which has victimized people not just in the Antelope Valley but around the United States, Simon said. Because the investigation is under way, he said he could not say much other than detectives have leads on suspects. But the best approach is to avoid being conned in the first place. Any mailing that asks for money should be evaluated with “extreme prudence,” Simon said. 160Want local news?Sign up for the Localist and stay informed Something went wrong. Please try again.subscribeCongratulations! You’re all set! LANCASTER – Legitimate-looking letters from an organization calling itself American Direct have conned thousands of dollars out of at least eight Antelope Valley residents who were told they won fake $250,000 lottery prizes, sheriff’s deputies say. The letters each contained a check for $4,800 – a purported advance from the winnings – but the victims were told to wire back $2,000 to cover insurance, handling and shipping of the full prize. After they sent the money, the victims found out the “advance” checks they got in the mail were not valid. “Unfortunately, lots of people are sending their money in to these people. We hope to get word out and stop any more people from losing their life savings,” said Deputy Kelly Simon, spokesman for the Lancaster sheriff’s station. last_img read more